SMOFlipid

Description

SMOFlipid is indicated in patients who needs intravenous nutrition to supply energy, essential fatty acids and omega-3 fatty acids.

Features

The unique, well-balanced lipid emulsion with purified natural fish oil
30% soybean oil as reliable source of essential fatty acids
30% medium-chain triglycerides (MCT) as source of rapidly available energy
25% olive oil for supply of monounsaturated fatty acids, especially oleic acid
15% fish oil provides ω-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)
Additionally vitamin E (approximately 200 mg a-tocopherol/L)
Fatty acid pattern with respect to saturated fatty acids, monounsaturated fatty acids, and essential fatty acids is similar to human milk
Extensive compatibility and stability data are available with a wide range of admixtures

Dosage

20% SMOF, (100ml, 250ml, 500ml) glass bottle,

Adult: Standard dose: 1.0 – 2.0 g fat/kg body wt
Neonates & infants: 0.5 – 1.0g fat/kg body wt/day, Followed by: 0.5 -1.0 g fat/kg body wt/day up to 3.0 g fat/kg body wt/day
Children: It is recommended not to exceed a daily dose of 3 g fat/kg body wt/day. Daily dose gradually increased during first week

Benefits

References

Piper SN et al. EJA 2009; 26: 1076-1082
Antebi H et al. JPEN 2004; 28:142 – 148
Schade I et al. Crit Care 2008; 12 (Suppl 2) S56–S57
Grimm H et al. EJN 2006; 45:55–60
Mertes N et al Ann. Nutr. Metab. 2006; 50:253-259
Tomsits E et al. Journal of Pediatric Gastroenterology & Nutrition 2010; 51:514-52
Klek S et al. Clin Nutr. 2012; epub ahead of print (http://dx.doi.org/10.1016/j.clnu.2012.06.011

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